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The Human Sexual Response

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Sexual Medicine

Abstract

Sex remains highly controversial and is a major driving force for the human brain [1]. The brain is the master seat control for all sexual behaviour. Human beings are sexual through a better part of their entire lives [1]. Sexuality of humans manifests in different ways with increasing age. Despite the controversies that surround human sex, for a majority of us, sex is a highly pleasurable process [2]. In the boarder context things, good sexual health definitely goes hand in hand with general wellness and good health [2]. But why engage in sex in the first place? Sex is definitely more wasteful compared to asexual modalities of reproduction [3]. Moreover sex and sexual reproduction are far less efficient in propagating a species as compared to asexual reproduction [3]. The exact answer however has eluded researchers for years despite excellent studies on animal sexual behaviour.

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References

  1. DeLamater J, Friedrich WN. Human sexual development. J Sex Res. 2002;39(1):10–4.

    Article  Google Scholar 

  2. Jannini EA, Fisher WA, Bitzer J, McMahon CG. Is sex just fun? How sexual activity improves health. J Sex Med. 2009;6:2640–8.

    Article  Google Scholar 

  3. Morran LT, Schmidt OG, Gelarden IA, Parris RC II, Lively CM. Running with the red queen: host–parasite coevolution selects for biparental sex. Science. 2011;333:216–8.

    Article  CAS  Google Scholar 

  4. Meston CM, Buss DM. Why humans have sex. Arch Sex Behav. 2007;36:477–507.

    Article  Google Scholar 

  5. Meston CM, Hamilton LD, Harte CB. Sexual motivation in women as a function of age. J Sex Med. 2009;6:3305–19.

    Article  Google Scholar 

  6. Georgiadis JR, Kringelbach ML. The human sexual response cycle: brain imaging evidence linking sex to other pleasures. Prog Neurobiol. 2012;98(1):49–81.

    Article  CAS  Google Scholar 

  7. Pfaus JG, Kippin TE, Coria-Avila G. What can animal models tell us about human sexual response? Ann Rev Sex Res. 2003;14(1):1–63.

    Google Scholar 

  8. Feiring C, Cleland CM, Simon VA. Abuse-specific self-schemas and self functioning: a prospective study of sexually abused youth. J Clin Child Adolesc Psychol. 2010;39:35–50.

    Article  Google Scholar 

  9. Ferretti A, Caulo M, Del Gratta C, Di Matteo R, Merla A, Montorsi F, Pizzella V, Pompa P, Rigatti P, Rossini PM, Salonia A, Tartaro A, Romani GL. Dynamics of male sexual arousal: distinct components of brain activation revealed by fMRI. NeuroImage. 2005;26:1086–96.

    Article  Google Scholar 

  10. Rizzolatti G, Craighero L. The mirror-neuron system. Annu Rev Neurosci. 2004;27:169–92.

    Article  CAS  Google Scholar 

  11. Moulier V, Mouras H, Pelegrini-Issac M, Glutron D, Rouxel R, Grandjean B, Bittoun J, Stoleru S. Neuroanatomical correlates of penile erection evoked by photographic stimuli in human males. NeuroImage. 2006;33:689–99.

    Article  CAS  Google Scholar 

  12. Mouras H, Stoleru S, Moulier V, Pelegrini-Issac M, Rouxel R, Grandjean B, Glutron D, Bittoun J. Activation of mirror-neuron system by erotic video clips predicts degree of induced erection: an fMRI study. NeuroImage. 2008;42:1142–50.

    Article  CAS  Google Scholar 

  13. Ponseti J, Bosinski HA, Wolff S, Peller M, Jansen O, Mehdorn HM, Buchel C, Siebner HR. A functional endophenotype for sexual orientation in humans. NeuroImage. 2006;33:825–33.

    Article  Google Scholar 

  14. Martinson FM. The sexual life of children. Westport, CT: Bergin and Garvey; 1994.

    Google Scholar 

  15. Bull JJ. Evolution of sex determining mechanisms. Menlo Park: The Benjamin/Cummings Publishing Company; 1983.

    Google Scholar 

  16. Masters WH, Johnson VE. Human sexual response. Boston, MA: Little, Brown & Company; 1966.

    Google Scholar 

  17. Robinson P. The modernization of sex. New York: Harper and Row; 1976.

    Google Scholar 

  18. Beach FA. Characteristics of masculine “sex drive”. In: Jones MR, editor. Nebraska symposium on motivation. Lincoln: University of Nebraska Press; 1956. p. 1–32.

    Google Scholar 

  19. Kinsey AC, Pomeroy WB, Martln CE, Gebhard PH. Sexual behavior in the human female. Philadelphia: W. B. Saunders Co; 1953.

    Google Scholar 

  20. Hackett G. The use of questionnaires to assess sexual function. Trends Urol Mens Health. 2017;8(1):17–20.

    Article  Google Scholar 

  21. Basson R. Human sex-response cycles. J Sex Marital Ther. 2001;27:33–43.

    Article  CAS  Google Scholar 

  22. Janssen E, Everaerd W, Spiering M, et al. Automatic processes and the appraisal of sexual stimuli: toward an information processing model of sexual arousal. J Sex Res. 2000;37:8–23.

    Article  Google Scholar 

  23. Laan E, van Driel EM, van Lunsen RHW. Genital responsiveness in healthy women with and without sexual arousal disorder. J Sex Med. 2008;5:1424–35.

    Article  Google Scholar 

  24. Goldhammer DL, McCabe MP. A qualitative exploration of the meaning and experience of sexual desire among partnered women. Can J Hum Sex. 2011;20(1–2):19–34.

    Google Scholar 

  25. Vannier SA, O’Sullivan LF. Sex without desire: characteristics of occasions of sexual compliance in young adults’ committed relationships. J Sex Res. 2010;47:429–39.

    Article  Google Scholar 

  26. Stole’ru S, Fonteille V, Corne’lis C, et al. Functional neuroimaging studies of sexual arousal and orgasm in healthy men and women: a review and meta-analysis. Neurosci Biobehav Rev. 2012;36:1481–509.

    Article  Google Scholar 

  27. American Psychiatric Association. Diagnostic and statistical manual of mental disorders (DSM-5®). San Francisco: American Psychiatric Publishing; 2013. p. 22.

    Book  Google Scholar 

  28. King M, Holt V, Nazareth I. Women’s view of their sexual difficulties: agreement and disagreement for the clinical diagnoses. Arch Sex Behav. 2007;36:281–8.

    Article  Google Scholar 

  29. Levin RJ. The human sexual response cycle. In: The textbook of clinical sexual medicine. Cham: Springer; 2017. p. 39–51.

    Chapter  Google Scholar 

  30. Havermans RC. How to tell where ‘liking’ ends and ‘wanting’ begins. Appetite. 2012;58:252–5.

    Article  Google Scholar 

  31. Smith KS, Berridge KC, Aldridge JW. Disentangling pleasure from incentive salience and learning signals in brain reward circuitry. Proc Natl Acad Sci U S A. 2011;108:E255–64.

    Article  CAS  Google Scholar 

  32. Mostafa T, El Khouly G, Hassan A. Pheromones in sex and reproduction: do they have a role in humans? J Adv Res. 2012;3:1–9.

    Article  CAS  Google Scholar 

  33. Loken LS, Wessberg J, Morrison I, McGlone F, Olausson H. Coding of pleasant touch by unmyelinated afferents in humans. Nat Neurosci. 2009;12:547–8.

    Article  Google Scholar 

  34. Michels L, Mehnert U, Boy S, Schurch B, Kollias S. The somatosensory representation of the human clitoris: an fMRI study. NeuroImage. 2010;49:177–84.

    Article  Google Scholar 

  35. Georgiadis JR, Reinders AA, Paans AM, Renken R, Kortekaas R. Men versus women on sexual brain function: prominent differences during tactile genital stimulation but not during orgasm. Hum Brain Mapp. 2009;30:3089–101.

    Article  Google Scholar 

  36. Miyagawa Y, Tsujimura A, Fujita K, Matsuoka Y, Takahashi T, Takao T, Takada S, Matsumiya K, Osaki Y, Takasawa M, Oku N, Hatazawa J, Kaneko S, Okuyama A. Differential brain processing of audiovisual sexual stimuli in men: comparative positron emission tomography study of the initiation and maintenance of penile erection during sexual arousal. NeuroImage. 2007;36:830–42.

    Article  Google Scholar 

  37. Ghazanfar AA, Santos LR. Primate brains in the wild: the sensory bases for social interactions. Nat Rev Neurosci. 2004;5:603–16.

    Article  CAS  Google Scholar 

  38. Childress AR, Ehrman RN, Wang Z, Li Y, Sciortino N, Hakun J, Jens W, Suh J, Listerud J, Marquez K, Franklin T, Langleben D, Detre J, O’Brien CP. Prelude to passion: limbic activation by unseen drug and sexual cues. PLoS One. 2008;3:e1506.

    Article  Google Scholar 

  39. Rupp HA, Wallen K. Sex differences in response to visual sexual stimuli: a review. Arch Sex Behav. 2008;37:206–18.

    Article  Google Scholar 

  40. Caspers S, Zilles K, Laird AR, Eickhoff SB. ALE meta-analysis of action observation and imitation in the human brain. NeuroImage. 2010;50:1148–67.

    Article  Google Scholar 

  41. Buhler M, Vollstadt-Klein S, Klemen J, Smolka MN. Does erotic stimulus presentation design affect brain activation patterns? Event-related vs blocked fMRI designs. Behav Brain Funct. 2008;4:30.

    Article  Google Scholar 

  42. Klucken T, Schweckendiek J, Merz CJ, Tabbert K, Walter B, Kagerer S, Vaitl D, Stark R. Neural activations of the acquisition of conditioned sexual arousal: effects of contingency awareness and sex. J Sex Med. 2009;6:3071–85.

    Article  Google Scholar 

  43. Savic I, Lindstrom P. PET and MRI show differences in cerebral asymmetry and functional connectivity between homo- and heterosexual subjects. Proc Natl Acad Sci U S A. 2008;105:9403–8.

    Article  CAS  Google Scholar 

  44. Clayton AH, Clavet GJ, McGarvey EL, Warnock JK, Weiss K. Assessment of sexual functioning during the menstrual cycle. J Sex Marital Ther. 1999;25:281–91.

    Article  CAS  Google Scholar 

  45. Mass R, Holldorfer M, Moll B, Bauer R, Wolf K. Why we haven’t died out yet: changes in women’s mimic reactions to visual erotic stimuli during their menstrual cycles. Horm Behav. 2009;55:267–71.

    Article  Google Scholar 

  46. Chivers ML, Seto MC, Blanchard R. Gender and sexual orientation differences in sexual response to sexual activities versus gender of actors in sexual films. J Pers Soc Psychol. 2007;93:1108–21.

    Article  Google Scholar 

  47. Graham CA. The DSM diagnostic criteria for female sexual arousal disorder. Arch Sex Behav. 2010;39(2):240–55.

    Article  Google Scholar 

  48. Dennerstein L, Lehert P, Guthrie J. The effects of the menopausal transition and biopsychosocial factors on well-being. Arch Womens Ment Health. 2002;5:15–22.

    Article  CAS  Google Scholar 

  49. Mah K, Binik YM. The nature of human orgasm: a critical review of major trends. Clin Psychol Rev. 2001;21:823–56.

    Article  CAS  Google Scholar 

  50. Warneke LB. A case of temporal lobe epilepsy with an orgasmic component. Can Psychiatr Assoc J. 1976;21(5):319–24.

    Article  CAS  Google Scholar 

  51. Georgiadis JR, Kortekaas R, Kuipers R, Nieuwenburg A, Pruim J, Reinders AATS, Holstege G. Regional cerebral blood flow changes associated with clitorally induced orgasm in healthy women. Eur J Neurosci. 2006;24:3305–16.

    Article  Google Scholar 

  52. Georgiadis JR, Reinders AA, van der Graaf FH, Paans AM, Kortekaas R. Brain activation during human male ejaculation revisited. Neuroreport. 2007;18:553–7.

    Article  Google Scholar 

  53. Levin RJ. Revisiting post-ejaculation refractory time-what we know and what we do not know in males and in females. J Sex Med. 2009;6:2376–89.

    Article  Google Scholar 

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Khan, S.D., Gunasekaran, K. (2019). The Human Sexual Response. In: Gunasekaran, K., Khan, S. (eds) Sexual Medicine . Springer, Singapore. https://doi.org/10.1007/978-981-13-1226-7_1

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  • DOI: https://doi.org/10.1007/978-981-13-1226-7_1

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