Anti-inflammatory benefits of ivy leaves

Ivy leaves are not only famous for cough remedies, liver detoxification but it also has a great effect in fighting inflammatory problems of the body. The medicinal ivy leaf extract has been tested for its anti-inflammatory properties. The marked reduction of inflammatory symptoms by ivy leaf extract shows the potential of this medicinal herb with anti-inflammatory, arthritis, rheumatism, gout.

Herbal ivy in nature:

Hedera helix (Linn) ivy belongs to the family Araliaceae and is found in hot, humid tropical climates. It is a woody, climbing wall, covering the walls with thick foliage. It is also grown as an ornamental plant.

In folk medicine, ivy leaves are used to treat benign warts and inflammation. Inflammation is a fundamental protective response. However, inflammation can be harmful in conditions such as life-threatening hypersensitivity reactions to insect bites, drugs, and toxins, and in chronic diseases such as rheumatoid arthritis, atherosclerosis, and fibrosis. lung and cancer. Inflammation has been shown to increase cancer and chronic risk.

Anti-inflammatory effects of ivy leaves:

The medicinal plant extracts of ivy leaves (Hedera helix) have been reported to have antioxidant, antispasmodic, and antiallergic properties. Effect of dry extract on respiratory function of children with chronic bronchial asthma and anticancer activity.

In an effort to find new herbal sources for the treatment of inflammation, current studies in ivy have been tested for its anti-inflammatory properties using 2% formalin to induce inflammation. Anti-inflammatory experiments were performed using non-steroidal anti-inflammatory drugs as reference drugs. The antiallergic properties of ivy leaf medicinal extracts were also monitored.

Swiss Albino rats (6-8 weeks old) of both sexes were used in the study. Animals of approximately equal age and weight were used for the experimental and control groups. For the preparation of the ivy leaf medicinal extract, the leaves of the plant were collected and identified in the botany department of the University of St. Joseph, Darjeeling. Leaves are washed with water. Use 10g ivy leaves, wash and crush. Add 15ml white wine, keep in refrigerator at 4° for 12 hours. The extract was then filtered through filter paper, then the filtrate was filtered through a Millipore filter and the final solution obtained was stored at 4° for further use.

Animals were divided into five groups of eight mice each (Group A, B, C, D and E). Twenty minutes before inflammation, group A mice were used as controls, and each group A animal received only intraperitoneal (i.p.) phosphate-buffered saline (PBS) (3 ml/kg). Groups B, C and D test rats received Hedera ethanol extract 2.5-7.5 ml/kg wt (25 μl, 50 μl and 75 μl per animal, respectively). Group E animals received a nonsteroidal anti-inflammatory drug (diclofenac) as a reference drug 100 mg/kg. Non-steroidal anti-inflammatory drugs have been used as they are non-biological anti-inflammatory drugs. Nonsteroidal anti-inflammatory drugs have been reported to suppress inflammation induced by various agents in experimental animal models. Nonsteroidal anti-inflammatory drugs are commonly used in the treatment or management of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis and for its anti-inflammatory and analgesic effects. Nonsteroidal anti-inflammatory drugs work to reduce inflammation, swelling, and pain in joints by inhibiting synthesis. The drug also affects polymorphonuclear leukocyte function in vitro, thereby reducing chemotaxis, toxic superoxide radical formation, oxygen free radical generation, and neutral protease production.

However, it can cause some side effects such as drowsiness. Although the anti-inflammatory, analgesic trial was successful, for its antitoxic activity further testing is needed in the future. The use of ivy leaf functional food ingredient extract for the treatment of inflammation and arthritis has opened up a safe, effective and cost-effective herbal treatment for these chronic diseases.

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